SUN Lab

Welcome to the Sun Lab

Welcome to our laboratory focused on developing statistical methods or computational tools for Digital Healthspan research. Our mission is: how early can we detect the loss of healthy function? This question drives our research to build human cell and tissue atlases from single-cell and spatial multi-omics data to identify which cell states change as function declines, where those changes occur, and which may serve as early warning signals; to develop causal statistical methods for digital models of cells, organs, and individuals, integrating molecular profiles, time-resolved experiments, and longitudinal clinical records; and to investigate how cellular changes contribute to organ dysfunction and estimate how an individual’s health trajectory might shift if an intervention started earlier or a different treatment was used. We use these approaches to study why people with the same diagnosis follow different trajectories, identify molecular subtypes of disease, and develop tools for early risk detection and disease monitoring. Our goal is to understand when, how, and for whom interventions could extend healthspan.

We are located at Xi’an Jiaotong University in Shaanxi, Xi’an. Please contact me if you are interested in joining us.